TARDBP

TARDBP蛋白，也称为TDP-43，是一种具有RRM1和RRM2的RNA结合因子，其结构包括N端的氨基末端、两个RNA识别区以及富含甘氨酸的C端。该蛋白通过结合GU重复序列，调节RNA的剪接过程，对神经元存活和神经退行性疾病中的蛋白质功能至关重要。TARDBP蛋白的突变或异常聚集与多种神经退行性疾病如ALS和FTLD相关。虽然其具体的信号通路尚未完全明确，但研究表明，TARDBP可能与其他蛋白或分子相互作用，形成复杂的信号网络，共同调控神经元的生存和功能，涉及细胞凋亡、自噬等信号转导途径。

热销产品

Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial

验证数据

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TARDBP Antibody

TARDBP Protein

TARDBP ELISA Kit

TARDBP Antibodies

TARDBP for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA023129GA01HU	TARDBP Antibody	Human,Mouse,Rat,Zebrafish	ELISA,WB,IHC,IF,IP
CSB-PA621652ESR1HU	TARDBP Antibody	Human, Mouse	ELISA, WB, IHC, IP
CSB-PA023129EA01HU	TARDBP Antibody	Human	ELISA, WB, IHC, IF
CSB-PA023129EB01HU	TARDBP Antibody, HRP conjugated	Human	ELISA
CSB-PA023129EC01HU	TARDBP Antibody, FITC conjugated	Human
CSB-PA023129ED01HU	TARDBP Antibody, Biotin conjugated	Human	ELISA

TARDBP Proteins

TARDBP Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-EP023129HU	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-YP023129HU	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	Yeast
CSB-EP023129HUe0	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-EP023129HU(A4)	Recombinant Human TAR DNA-binding protein 43 (TARDBP)	E.coli
CSB-EP023129HU2	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-EP023129HU(A4)a0	Recombinant Human TAR DNA-binding protein 43 (TARDBP)	E.coli