TMPRSS2
TMPRSS2（Transmembrane Serine Protease 2）是一种跨膜丝氨酸蛋白酶，TMPRSS2主要存在于上皮细胞中，特别是在肺部、肠道和前列腺等组织中表达较高。它的一个重要作用是剪切和活化其他蛋白，尤其是病毒蛋白或其他蛋白前体。在病毒感染中，比如在SARS-CoV-2（导致COVID-19的病毒）感染中，TMPRSS2蛋白可以促进病毒进入宿主细胞。在COVID-19研究中，TMPRSS2被认为参与了SARS-CoV-2病毒进入上皮细胞的过程，因此针对TMPRSS2的研究可能有助于发展针对病毒入侵的治疗方法。
热销产品
Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial (Active)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Recombinant Human TMPRSS2 His tag protein (CSB-YP023924HU) enzyme activity is measured by its ability to cleave fluorogenic peptide substrate(Boc-Gln-Ala-Arg-AMC), The Km is 21.93μM.
Activity
Measured by Camostat Mesylate inhibit ratio on TMPRSS2 (CSB-YP023924HU), which can cleave fluorogenic peptide substrate (Boc-Gln-Ala-Arg-AMC). The Camostat Mesylate inhibit EC50 is 0.03347-0.07945μM.
TMPRSS2 Antibodies
TMPRSS2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA971239 | TMPRSS2 Antibody | Human | ELISA, WB |
TMPRSS2 Proteins
TMPRSS2 Proteins for Homo sapiens (Human)
TMPRSS2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-BP884918MO CSB-MP884918MO CSB-EP884918MO-B |
Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP884918MO | Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial | E.coli |
| CSB-YP884918MO | Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial | Yeast |
| CSB-YP884918MO | Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial | Yeast |
| CSB-YP884918MOc7 | Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial | Yeast |
