TRIB3
TRIB3，即Tribbles同源蛋白3，它是一种在多种细胞类型中表达的假激酶。TRIB3能够与多种蛋白质相互作用，参与调节细胞的代谢、应激反应、炎症以及细胞周期等过程。其作用机制包括通过与Akt等蛋白结合并影响其活性，进而调控细胞的生存和代谢。在信号通路方面，TRIB3与PI3K-AKT-mTOR信号通路密切相关，它通过抑制Akt的磷酸化和活性，参与调节细胞的代谢和存活。在生物学意义上，TRIB3在糖尿病、癌症、心血管疾病和神经系统疾病的发生发展中可能发挥重要作用。研究表明，TRIB3的表达受多种应激反应的调控，如营养缺乏、缺氧、内质网应激等，提示其在细胞应激反应中的"桥梁"作用。
热销产品
Recombinant Mouse Tribbles homolog 3 (Trib3) (CSB-EP818358MO)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TRIB3 Antibody (CSB-PA847220LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA847220LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA847220LA01HU at dilution of 1:100
TRIB3 Antibodies
TRIB3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA024446GA01HU | TRIB3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA120599 | TRIB3 Antibody | Human | ELISA,IHC |
| CSB-PA592034 | TRIB3 Antibody | Human | ELISA,IHC |
| CSB-PA847220LA01HU | TRIB3 Antibody | Human | ELISA, IHC |
| CSB-PA847220LB01HU | TRIB3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA847220LC01HU | TRIB3 Antibody, FITC conjugated | Human | |
| CSB-PA847220LD01HU | TRIB3 Antibody, Biotin conjugated | Human | ELISA |
TRIB3 Proteins
TRIB3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP847220HU CSB-EP847220HU CSB-BP847220HU CSB-MP847220HU CSB-EP847220HU-B |
Recombinant Human Tribbles homolog 3 (TRIB3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
