TRPM8
TRPM8，即瞬时受体电位M8离子通道，它在多种哺乳动物中表达，尤其是感觉神经元中。TRPM8的作用机制是作为冷感受器，在温度下降时被激活，允许钙离子和钠离子流入细胞，从而引发冷感觉信号的传导。TRPM8对于动物感知环境温度变化、适应低温环境具有重要意义。此外，TRPM8还与某些疾病的发生发展有关，如前列腺癌、膀胱癌和乳腺癌。2021年诺贝尔生理学或医学奖授予了对温度敏感的TRP通道的研究，这进一步凸显了TRPM8等通道在感知热和冷以及适应环境温度中的重要性。
热销产品
验证数据
CSB-MP768757HU1 is detected by Mouse anti-6*His monoclonal antibody.
TRPM8 Recombinant Monoclonal Antibody (CSB-RA186773A0HU)
验证数据
IHC image of CSB-RA186773A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
TRPM8 Antibodies
TRPM8 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA768757LA01HU | TRPM8 Antibody | Human | ELISA, IHC, IF |
| CSB-PA768757ESR1HU | TRPM8 Antibody | Human | ELISA, IHC |
| CSB-PA969456 | TRPM8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA072616 | TRPM8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA186773A0HU | TRPM8 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
TRPM8 Proteins
TRPM8 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP768757HU CSB-EP768757HU CSB-BP768757HU CSB-MP768757HU CSB-EP768757HU-B |
Recombinant Human Transient receptor potential cation channel subfamily M member 8 (TRPM8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP768757HU1 | Recombinant Human Transient receptor potential cation channel subfamily M member 8 (TRPM8) , partial-VLPs | Mammalian cell |
