Tnfrsf13b

TNFRSF13B，即肿瘤坏死因子受体超家族成员13B，别名B细胞活化因子（BAFF）、TALL-1、CD267、TACI配体等。它是一种主要由单核细胞、树突状细胞及T细胞产生的细胞因子，属于肿瘤坏死因子超家族成员。TNFRSF13B在免疫应答中起重要作用，尤其是促进B细胞的成熟和分化，并与自身免疫密切相关。其作用机制涉及与其受体TACI、BCMA和BAFFR等结合，激活下游的信号传导途径，如NF-κB、JAK/STAT等，进而影响B细胞的存活、增殖和分化。TNFRSF13B在生物学上的意义非常广泛，它参与了多种生理和病理过程的调节。在正常生理条件下，TNFRSF13B对于维持B细胞稳态和抗体产生至关重要。在病理条件下，TNFRSF13B的异常表达或功能失调与多种自身免疫性疾病的发生发展有关，如系统性红斑狼疮、类风湿关节炎等。此外，TNFRSF13B还可能参与某些B细胞淋巴瘤的发展。因此，TNFRSF13B是免疫学研究和相关疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (TNFRSF13B), partial (Active) (CSB-AP002301HU)

验证数据

TNFRSF13B Antibody (CSB-PA006292)

验证数据

Western Blot analysis of 3T3 cells using CD267 Polyclonal Antibody

Western Blot analysis of NIH-3T3 cells using CD267 Polyclonal Antibody

Tnfrsf13b Antibody

Tnfrsf13b Protein

Tnfrsf13b ELISA Kit

Tnfrsf13b Antibodies

Tnfrsf13b for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA023971GA01HU	TNFRSF13B Antibody	Human	ELISA,WB
CSB-PA023971DSR2HU	TNFRSF13B Antibody	Human	ELISA, IHC
CSB-PA006292	TNFRSF13B Antibody	Human	WB, ELISA

Tnfrsf13b Proteins

Tnfrsf13b Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP023971HU1 CSB-EP023971HU1 CSB-BP023971HU1 CSB-MP023971HU1 CSB-EP023971HU1-B	Recombinant Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP002301HU	Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (TNFRSF13B), partial (Active)	E.Coli
CSB-CF023971HU	Recombinant Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B)	in vitro E.coli expression system

Tnfrsf13b Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP863678MO CSB-EP863678MO CSB-BP863678MO CSB-MP863678MO CSB-EP863678MO-B	Recombinant Mouse Tumor necrosis factor receptor superfamily member 13B (Tnfrsf13b), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli