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Ube2b

Ubiquitin-conjugating enzyme E2 B is a protein in humans that is encoded by UBE2B gene. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination.

Ube2b Antibodies

Ube2b for Homo sapiens (Human)

Ube2b Proteins

Ube2b Proteins for Mus musculus (Mouse)

Ube2b Proteins for Homo sapiens (Human)

Ube2b Proteins for Oryctolagus cuniculus (Rabbit)

Ube2b Proteins for Rattus norvegicus (Rat)

Ube2b Proteins for Bos taurus (Bovine)