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VPS29

Vacuolar protein sorting-associated protein 29 is a protein in humans that is encoded by VPS29 gene. Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.

VPS29 Antibodies

VPS29 for Homo sapiens (Human)

VPS29 Proteins

VPS29 Proteins for Rattus norvegicus (Rat)

VPS29 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

VPS29 Proteins for Bos taurus (Bovine)

VPS29 Proteins for Dictyostelium discoideum (Slime mold)

VPS29 Proteins for Gallus gallus (Chicken)

VPS29 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

VPS29 Proteins for Pongo abelii (Sumatran orangutan)

VPS29 Proteins for Xenopus laevis (African clawed frog)

VPS29 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

VPS29 Proteins for Arabidopsis thaliana (Mouse-ear cress)

VPS29 Proteins for Mus musculus (Mouse)

VPS29 Proteins for Homo sapiens (Human)

VPS29 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)