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WEE2

Wee1-like protein kinase 2 is a protein in humans that is encoded by WEE2 gene. Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

WEE2 Antibodies

WEE2 for Homo sapiens (Human)

WEE2 Proteins

WEE2 Proteins for Sus scrofa (Pig)

WEE2 Proteins for Gallus gallus (Chicken)

WEE2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

WEE2 Proteins for Homo sapiens (Human)

WEE2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

WEE2 Proteins for Ailuropoda melanoleuca (Giant panda)

WEE2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

WEE2 Proteins for Mus musculus (Mouse)