ZNRF3
ZNRF3（Zinc and Ring Finger 3）属于RING（Really Interesting New Gene）指环蛋白家族，它包含一个RING结构域，这是一个特定类型的结构域，具有E3泛素连接酶活性。ZNRF3的主要功能之一是调节细胞膜上受体和蛋白质的稳定性。它通过将泛素分子附加到目标蛋白质上，标记它们以进行降解。这个过程被称为泛素化，是细胞对于调控蛋白质水平和信号通路的重要机制之一。在癌症研究领域，ZNRF3与Wnt信号通路的调控有关，该信号通路在多种癌症中起关键作用。
热销产品
Recombinant Human E3 ubiquitin-protein ligase ZNRF3(ZNRF3),partial (Active) CSB-MP890933HU
验证数据
SDS
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELISA
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ZNRF3 at 5 μg/ml can bind Human RSPO2 (CSB-MP751021HU1(M)), the EC50 is 5.091-6.991 ng/mL.
ZNRF3 Antibodies
ZNRF3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA890933HA01HU | ZNRF3 Antibody | Human | ELISA, IF |
| CSB-PA890933HB01HU | ZNRF3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA890933HC01HU | ZNRF3 Antibody, FITC conjugated | Human | |
| CSB-PA890933HD01HU | ZNRF3 Antibody, Biotin conjugated | Human | ELISA |
ZNRF3 Proteins
ZNRF3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP716332MO CSB-EP716332MO CSB-BP716332MO CSB-MP716332MO CSB-EP716332MO-B |
Recombinant Mouse Zinc/RING finger protein 3 (Znrf3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ZNRF3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP890933HU-B |
Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | In Vivo Biotinylation in E.coli |
| CSB-EP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | E.coli |
| CSB-EP890933HUe1 | Recombinant Human Zinc/RING finger protein 3 (ZNRF3),Partial | E.coli |
| CSB-BP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | Baculovirus |
| CSB-YP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | Yeast |
| CSB-MP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial (Active) | Mammalian cell |
