ppard
PPARD，即过氧化物酶体增殖物激活受体δ，别名PPARδ、NR1C2。PPARD是一种核受体，属于PPAR家族成员之一，由人体细胞自身的基因编码。PPARD在多种组织中都有表达，尤其在心脏、骨骼肌、肝脏和脂肪组织中表达量较高。其作用机制主要是通过与特定的配体结合，如脂肪酸和其衍生物，激活受体，形成异源二聚体与DNA上的PPAR响应元件（PPREs）结合，调控下游基因的表达。PPARD在生物学上的意义非常广泛，它参与调节脂肪酸的氧化、能量代谢、炎症反应和细胞分化等多种生理过程。PPARD的激活可以促进脂肪酸的氧化，提高能量效率，同时抑制炎症反应，对心血管健康具有保护作用。此外，PPARD还与肥胖、糖尿病、动脉粥样硬化等代谢性疾病的发生发展密切相关。PPARD的激动剂，如贝特类药物，已被用于治疗高脂血症和心血管疾病，显示出其在代谢调节中的潜在治疗价值。因此，PPARD是代谢性疾病研究和治疗中的一个重要靶点。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PPARD Monoclonal Antibody (CSB-MA294484)
验证数据
Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using PPAR Delta Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Mouse Brain Tissue using PPAR Delta Mouse mAb diluted at 1:200.
ppard Antibodies
ppard for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA018423GA01HU | PPARD Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA565092 | PPARD Antibody | Human,Mouse | ELISA,WB |
| CSB-MA294484 | PPARD Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA662949 | PPARD Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
ppard Proteins
ppard Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018423MO CSB-EP018423MO CSB-BP018423MO CSB-MP018423MO CSB-EP018423MO-B |
Recombinant Mouse Peroxisome proliferator-activated receptor delta (Ppard) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ppard Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018423XBE CSB-EP018423XBE CSB-BP018423XBE CSB-MP018423XBE CSB-EP018423XBE-B |
Recombinant Xenopus laevis Peroxisome proliferator-activated receptor delta (ppard) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ppard Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018423DO CSB-EP018423DO CSB-BP018423DO CSB-MP018423DO CSB-EP018423DO-B |
Recombinant Dog Peroxisome proliferator-activated receptor delta (PPARD) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ppard Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP018423HU1 | Recombinant Human Peroxisome proliferator-activated receptor delta (Ppard), partial | E.coli |
| CSB-EP018423HU2 | Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial | E.coli |
| CSB-EP018423HU2 | Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial | E.coli |
| CSB-EP018423HU2a2 | Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial | E.coli |
