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  4. Human Inter-alpha-trypsin inhibitor heavy chain H2(ITIH2) ELISA kit

Human Inter-alpha-trypsin inhibitor heavy chain H2(ITIH2) ELISA kit

  • 中文名称：
    人间α-胰蛋白酶抑制剂重链H2(ITIH2)酶联免疫试剂盒
  • 货号：
    CSB-EL011895HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human ITIH2 ELISA Kit was designed for the quantitative measurement of Human ITIH2 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 3.12 μg/mL-200 μg/mL and the sensitivity is 0.78 μg/mL.

  • 别名：
    AI747202 ELISA Kit; H2P ELISA Kit; IGHEP2 ELISA Kit; Inter alpha (globulin) inhibitor H2 ELISA Kit; Inter alpha globulin inhibitor H2 polypeptide ELISA Kit; Inter alpha trypsin inhibitor complex component II ELISA Kit; Inter alpha trypsin inhibitor heavy chain H2 ELISA Kit; Inter-alpha-inhibitor heavy chain 2 ELISA Kit; Inter-alpha-trypsin inhibitor complex component II ELISA Kit; Inter-alpha-trypsin inhibitor heavy chain H2 ELISA Kit; Intin2 ELISA Kit; ITI HC2 ELISA Kit; ITI heavy chain H2 ELISA Kit; ITI-HC2 ELISA Kit; Itih 2 ELISA Kit; Itih2 ELISA Kit; ITIH2_HUMAN ELISA Kit; OTTHUMP00000019058 ELISA Kit; OTTHUMP00000019059 ELISA Kit; OTTMUSP00000012019 ELISA Kit; RP23 119N4.3 ELISA Kit; Serum derived hyaluronan associated protein ELISA Kit; Serum-derived hyaluronan-associated protein ELISA Kit; SHAP ELISA Kit
  • 缩写：
    ITIH2
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    3.12 μg/mL-200 μg/mL
  • 灵敏度：
    0.78 μg/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cell Biology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human ITIH2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:5Average %91
    Range %86-94
    1:10Average %97
    Range %90-104
    1:20Average %101
    Range %96-107
    1:40Average %89
    Range %84-94
  • 回收率：
    The recovery of human ITIH2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9088-95
    EDTA plasma (n=4)10297-107
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    μg/mlOD1OD2AverageCorrected
    2002.439 2.555 2.497 2.312
    1001.867 1.728 1.798 1.613
    501.221 1.265 1.243 1.058
    250.751 0.757 0.754 0.569
    12.50.412 0.422 0.417 0.232
    6.250.318 0.336 0.327 0.142
    3.120.272 0.281 0.277 0.092
    00.183 0.186 0.185
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
  • 基因功能参考文献：
    1. It forms complex with hyaluronan and the comlex is a functional molecule involved in inflammation. PMID: 20297716
    2. TSG-6 acts as cofactor and catalyst in the production of IalphaI heavy chain x hyaluronan complexes PMID: 15840581
    3. Leukocytes infiltrated to the synovium were strongly positive for hyaluronic acid, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in inflammation. PMID: 16702221
    4. Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor. PMID: 18382897
    5. serum-derived hyaluronan-associated protein-hyaluronan complex has a role in progression of ovarian cancer PMID: 18425383

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    ITIH family
  • 组织特异性：
    Plasma.
  • 数据库链接：

    HGNC: 6167

    OMIM: 146640

    KEGG: hsa:3698

    STRING: 9606.ENSP00000351190

    UniGene: Hs.75285