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Cleaved-ITIH2 (D702) Antibody

  • 货号：
    CSB-PA000075
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using Cleaved-ITI-H2 (D702) Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P19823
  • 基因名：
    ITIH2
  • 别名：
    AI747202 antibody; H2P antibody; IGHEP2 antibody; Inter alpha (globulin) inhibitor H2 antibody; Inter alpha globulin inhibitor H2 polypeptide antibody; Inter alpha trypsin inhibitor complex component II antibody; Inter alpha trypsin inhibitor heavy chain H2 antibody; Inter-alpha-inhibitor heavy chain 2 antibody; Inter-alpha-trypsin inhibitor complex component II antibody; Inter-alpha-trypsin inhibitor heavy chain H2 antibody; Intin2 antibody; ITI HC2 antibody; ITI heavy chain H2 antibody; ITI-HC2 antibody; Itih 2 antibody; Itih2 antibody; ITIH2_HUMAN antibody; OTTHUMP00000019058 antibody; OTTHUMP00000019059 antibody; OTTMUSP00000012019 antibody; RP23 119N4.3 antibody; Serum derived hyaluronan associated protein antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ITI-H2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
  • 基因功能参考文献：
    1. It forms complex with hyaluronan and the comlex is a functional molecule involved in inflammation. PMID: 20297716
    2. TSG-6 acts as cofactor and catalyst in the production of IalphaI heavy chain x hyaluronan complexes PMID: 15840581
    3. Leukocytes infiltrated to the synovium were strongly positive for hyaluronic acid, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in inflammation. PMID: 16702221
    4. Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor. PMID: 18382897
    5. serum-derived hyaluronan-associated protein-hyaluronan complex has a role in progression of ovarian cancer PMID: 18425383

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    ITIH family
  • 组织特异性：
    Plasma.
  • 数据库链接：

    HGNC: 6167

    OMIM: 146640

    KEGG: hsa:3698

    STRING: 9606.ENSP00000351190

    UniGene: Hs.75285