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  4. Human Statherin(STATH) ELISA kit

Human Statherin(STATH) ELISA kit

  • 中文名称：
    人富酪蛋白(STATH)酶联免疫试剂盒
  • 货号：
    CSB-EL022817HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human STATH ELISA Kit was designed for the quantitative measurement of Human STATH protein in serum, plasma, tissue homogenates, saliva. It is a Sandwich ELISA kit, its detection range is 78 ng/mL-5000 ng/mL and the sensitivity is 19.5 ng/mL.

  • 别名：
    STAT_HUMAN ELISA Kit; STATH ELISA Kit; Statherin ELISA Kit; Statherin precursor ELISA Kit; STR ELISA Kit
  • 缩写：
    STATH
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates, saliva
  • 检测范围：
    78 ng/mL-5000 ng/mL
  • 灵敏度：
    19.5 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cell Biology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human STATH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %90
    Range %87-93
    1:2Average %95
    Range %91-104
    1:4Average %86
    Range %82-92
    1:8Average %96
    Range %92-101
  • 回收率：
    The recovery of human STATH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9489-97
    EDTA plasma (n=4)9994-104
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    50002.751 2.651 2.701 2.547
    25001.829 1.729 1.779 1.625
    12501.087 1.067 1.077 0.923
    6250.589 0.579 0.584 0.430
    312.50.382 0.372 0.377 0.223
    1560.265 0.255 0.260 0.106
    780.209 0.207 0.208 0.054
    00.154 0.153 0.154 　
  • 数据处理：
  • 货期：
    3-5 working days

引用文献

产品评价

靶点详情

  • 功能：
    Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.
  • 基因功能参考文献：
    1. The total protein and statherin in the in-vivo AEP were different between eroded and non-eroded tooth surfaces of the same patient PMID: 28837608
    2. effects of statherin on intracellular calcium level and its subsequent related molecular alterations would give us new pathogenic aspect in oral carcinogenesis PMID: 25128293
    3. phenylalanine orientations in statherin bound to hydroxyapatite surfaces PMID: 22563672
    4. Data show that the full characterization of the statherin peptides generated facilitates the elucidation of their novel functional roles in the oral and gastro-intestinal environment. PMID: 20731414
    5. insight into the molecular interactions of statherin with hydroxyapatite surfaces PMID: 19678690
    6. inhibits calcium phosphate precipitation PMID: 12060866
    7. results suggest that a layer rich in statherin forms at the interface of saliva and air, and that the surface rheology developed is dependent upon protein interactions mediated by calcium PMID: 15769251
    8. In conclusion, statherin induces transition to yeast of Candida albicans hyphae and may thus contribute to the oral defense against candidiasis. PMID: 19799638

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Histatin/statherin family
  • 组织特异性：
    Secreted by parotid and submandibular glands.
  • 数据库链接：

    HGNC: 11369

    OMIM: 184470

    KEGG: hsa:6779

    STRING: 9606.ENSP00000246895

    UniGene: Hs.654495