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STATH Antibody

  • 货号:
    CSB-PA022817GA01HU
  • 规格:
    ¥3,900
  • 其他:

产品详情

  • Uniprot No.:
    P02808
  • 基因名:
    STATH
  • 别名:
    STAT_HUMAN antibody; STATH antibody; Statherin antibody; Statherin precursor antibody; STR antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Human STATH
  • 免疫原种属:
    Homo sapiens (Human)
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.
  • 基因功能参考文献:
    1. The total protein and statherin in the in-vivo AEP were different between eroded and non-eroded tooth surfaces of the same patient PMID: 28837608
    2. effects of statherin on intracellular calcium level and its subsequent related molecular alterations would give us new pathogenic aspect in oral carcinogenesis PMID: 25128293
    3. phenylalanine orientations in statherin bound to hydroxyapatite surfaces PMID: 22563672
    4. Data show that the full characterization of the statherin peptides generated facilitates the elucidation of their novel functional roles in the oral and gastro-intestinal environment. PMID: 20731414
    5. insight into the molecular interactions of statherin with hydroxyapatite surfaces PMID: 19678690
    6. inhibits calcium phosphate precipitation PMID: 12060866
    7. results suggest that a layer rich in statherin forms at the interface of saliva and air, and that the surface rheology developed is dependent upon protein interactions mediated by calcium PMID: 15769251
    8. In conclusion, statherin induces transition to yeast of Candida albicans hyphae and may thus contribute to the oral defense against candidiasis. PMID: 19799638

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  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    Histatin/statherin family
  • 组织特异性:
    Secreted by parotid and submandibular glands.
  • 数据库链接:

    HGNC: 11369

    OMIM: 184470

    KEGG: hsa:6779

    STRING: 9606.ENSP00000246895

    UniGene: Hs.654495