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AGO4 Antibody

  • 货号：
    CSB-PA864031LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of SH-SY5Y cells with CSB-PA864031LA01HU-IF at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) AGO4 Polyclonal antibody
  • Uniprot No.：
    Q9HCK5
  • 基因名：
  • 别名：
    Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4), AGO4, EIF2C4 KIAA1567
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein argonaute-4 protein (716-861aa)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，AGO4 Antibody (CSB-PA864031LA01HU)，的标记方式是Non-conjugated。对于AGO4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA864031LB01HU AGO4 Antibody, HRP conjugated ELISA
    FITC CSB-PA864031LC01HU AGO4 Antibody, FITC conjugated
    Biotin CSB-PA864031LD01HU AGO4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:100-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
  • 基因功能参考文献：
    1. Chimeras with Ago4 N-terminal domains were defective in RISC activation & sometimes also in RNA loading. This highlights the pleiotropic role of the Ago N domain & emphasizes the unique position of human Ago4 within the Ago protein family. PMID: 23748378
    2. EIF2C4 protein is expressed in differentiating and terminally differentiated N-type cells more than in S- and I-type cells PMID: 19393748
  • 亚细胞定位：
    Cytoplasm, P-body.
  • 蛋白家族：
    Argonaute family, Ago subfamily
  • 数据库链接：

    HGNC: 18424

    OMIM: 607356

    KEGG: hsa:192670

    STRING: 9606.ENSP00000362306

    UniGene: Hs.744858