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AGTPBP1 Antibody

  • 中文名称：
    AGTPBP1兔多克隆抗体
  • 货号：
    CSB-PA001464GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UPW5
  • 基因名：
    AGTPBP1
  • 别名：
    CCP1 antibody; 1700020N17Rik antibody; 2310001G17Rik antibody; 2900054O13Rik antibody; 4930445M19Rik antibody; 5730402G09Rik antibody; AGTPBP 1 antibody; AGTPBP1 antibody; ATP/GTP binding protein 1 antibody; ATP/GTP-binding protein 1 antibody; BB114605 antibody; Carboxypeptidase tubulin antibody; CBPC1_HUMAN antibody; Cytosolic carboxypeptidase 1 antibody; DKFZp686M20191 antibody; KIAA1035 antibody; MGC90651 antibody; mKIAA1035 antibody; Nervous system nuclear protein induced by axotomy antibody; Nervous system nuclear protein induced by axotomy protein 1 homolog antibody; nmf243 antibody; NNA1 antibody; OTTHUMP00000021581 antibody; OTTHUMP00000063553 antibody; pcd antibody; Purkinje cell degeneration antibody; RP11-30C23.1 antibody; Soluble carboxypeptidase antibody; Tubulinyl Tyr carboxypeptidase antibody; Tyrosine carboxypeptidase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human AGTPBP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.
  • 基因功能参考文献：
    1. we identified seven new putative CCP1 substrates, all of them harboring acidic amino acids in their gene-encoded C terminus PMID: 25381060
    2. Data indicate that a functional nuclear export signals (NESs) in CCP1 that mediates direct binding to the export receptor CRM1. PMID: 23242554
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytosol. Nucleus. Mitochondrion.
  • 蛋白家族：
    Peptidase M14 family
  • 数据库链接：

    HGNC: 17258

    OMIM: 606830

    KEGG: hsa:23287

    STRING: 9606.ENSP00000365251

    UniGene: Hs.719980