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ARHGAP20 Antibody

  • 中文名称：
    ARHGAP20兔多克隆抗体
  • 货号：
    CSB-PA002021GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9P2F6
  • 基因名：
    ARHGAP20
  • 别名：
    ARHGAP20 antibody; KIAA1391 antibody; Rho GTPase-activating protein 20 antibody; Rho-type GTPase-activating protein 20 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ARHGAP20
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
  • 基因功能参考文献：
    1. The similar expression profiles of ARHGAP20 in 13q14 and 11q22-23 deleted CLL cases suggest a molecular connection and an intriguing mechanism of regulation PMID: 21500311
    2. human KIAA1391 gene and mouse Kiaa1391 gene encode RhoGAP proteins with RA domain and two ANXL repeats PMID: 14532992
    3. RA-RhoGAP transduces a signal from Rap1 to Rho and regulates the neurite outgrowth PMID: 16014623
  • 相关疾病：
    A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).
  • 组织特异性：
    Expressed predominantly in the brain. Lower expression is found in lymph nodes.
  • 数据库链接：

    HGNC: 18357

    OMIM: 609568

    KEGG: hsa:57569

    STRING: 9606.ENSP00000260283

    UniGene: Hs.6136