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  4. ARHGEF10L Antibody

ARHGEF10L Antibody

  • 中文名称：
    ARHGEF10L兔多克隆抗体
  • 货号：
    CSB-PA002042GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9HCE6
  • 基因名：
    ARHGEF10L
  • 别名：
    ARGAL_HUMAN antibody; ARHGEF10L antibody; GrinchGEF antibody; KIAA1626 antibody; Rho guanine nucleotide exchange factor 10-like protein antibody; RP11-473A10.1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Human ARHGEF10L
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.
  • 基因功能参考文献：
    1. Inherited variants in ARHGEF10L and AKAP6, with potential transcriptional regulatory function and association with Epithelial ovarian cancer risk, warrant investigation in independent Epithelial ovarian cancer study populations. PMID: 29979793
    2. In intact cells, GrinchGEF induced specifically Rho activation and enhanced RhoA-C-specific downstream effects. PMID: 16112081
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Detected in heart, liver, skeletal muscle, kidney and pancreas.
  • 数据库链接：

    HGNC: 25540

    OMIM: 612494

    KEGG: hsa:55160

    STRING: 9606.ENSP00000355060

    UniGene: Hs.443460