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ARSG Antibody

  • 货号：
    CSB-PA002150LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ARSG antibody at 8µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 58 kDa
      Observed band size: 58 kDa
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA002150LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA002150LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ARSG Polyclonal antibody
  • Uniprot No.：
    Q96EG1
  • 基因名：
    ARSG
  • 别名：
    Arsg antibody; ARSG_HUMAN antibody; Arylsulfatase G antibody; Arylsulfatase G precursor antibody; ASG antibody; KIAA1001 antibody; PRO1777 antibody; UNQ839 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Arylsulfatase G protein (17-525AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ARSG Antibody (CSB-PA002150LA01HU)，的标记方式是Non-conjugated。对于ARSG Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA002150LB01HU ARSG Antibody, HRP conjugated ELISA
    FITC CSB-PA002150LC01HU ARSG Antibody, FITC conjugated
    Biotin CSB-PA002150LD01HU ARSG Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Displays arylsulfatase activity at acidic pH towards artificial substrates, such as p-nitrocatechol sulfate and also, but with a lower activity towards p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate. Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.
  • 基因功能参考文献：
    1. This study provide further support for a role of ARSG variants in task-specific dystonia, especially writer's cramp. PMID: 25825126
    2. Genome-wide significance with musician's dystonia was observed for an intronic variant in the arylsulfatase G (ARSG) gene (rs11655081; P = 3.95 x 10(-9) ; odds ratio [OR], 4.33; 95% confidence interval [CI], 2.66-7.05). PMID: 24375517
    3. ARSG is differentially expressed, processed, and transported in tissues involving a membrane-associated pre-lysosomal precursor. PMID: 25135642
    4. Consistent genetic factors for ATP2B1, CSK, ARSG and CSMD1 were present, which have been shown to be associated with high blood pressure and hypertension in two Korean cohorts. PMID: 19960030
    5. molecular cloning and biochemical characterization of Arylsulfatase G [ARSG] PMID: 12461688
    6. Arylsulfatase G is a novel lysosomal sulfatase and its expression is tissue-specific with highest expression in liver, kidney, and pancreas PMID: 18283100

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  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    Sulfatase family
  • 组织特异性：
    Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
  • 数据库链接：

    HGNC: 24102

    OMIM: 610008

    KEGG: hsa:22901

    STRING: 9606.ENSP00000407193

    UniGene: Hs.437249