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ASE1 Antibody

  • 中文名称：
    ASE1兔多克隆抗体
  • 货号：
    CSB-PA342670XA01SVG
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: ASE1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 27 kDa
      Observed band size: 27 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P50275
  • 基因名：
    ASE1
  • 别名：
    Anaphase spindle elongation protein ASE1 YOR058C YOR29-09
  • 反应种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ASE1 protein (43-223aa)
  • 免疫原种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Affinity-chromatography
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for anaphase spindle elongation.
  • 基因功能参考文献：
    1. When yeast cells were treated with hydroxyurea to block DNA synthesis and induce replication stress, we found that Ase1, a conserved spindle midzone protein, appeared as two short protein isoforms in addition to the full-length protein. PMID: 24768052
    2. the requirement of CDK for phosphorylation of the spindle midzone component Ase1p and its significance to spindle assembly PMID: 21558801
    3. Ase1p and Cin8p affect nuclear positioning through astral micro-tubule-dependent mechanisms. PMID: 17495529
    4. A pathway regulating IPL1 and the spindle midzone protein Ase1 regulates spindle assembly. PMID: 17765685
    5. Review identifies Ase1 as a key Cdc14 substrate and elucidates the coordination of spindle midzone assembly with metaphase to anaphase transition. PMID: 18235228

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    MAP65/ASE1 family
  • 数据库链接：

    KEGG: sce:YOR058C

    STRING: 4932.YOR058C