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ASZ1 Antibody

  • 货号：
    CSB-PA845159LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA845159LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA845159LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: Rat brain tissue
      All lanes: ASZ1 antibody at 2.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 54, 53 kDa
      Observed band size: 54 kDa
    • Immunofluorescent analysis of HepG2 cells using CSB-PA845159LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ASZ1 Polyclonal antibody
  • Uniprot No.：
    Q8WWH4
  • 基因名：
    ASZ1
  • 别名：
    ASZ1 antibody; ALP1 antibody; ANKL1 antibody; C7orf7 antibody; GASZAnkyrin repeat antibody; SAM and basic leucine zipper domain-containing protein 1 antibody; Ankyrin-like protein 1 antibody; Germ cell-specific ankyrin antibody; SAM and basic leucine zipper domain-containing protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ASZ1 Antibody (CSB-PA845159LA01HU)，的标记方式是Non-conjugated。对于ASZ1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA845159LB01HU ASZ1 Antibody, HRP conjugated ELISA
    FITC CSB-PA845159LC01HU ASZ1 Antibody, FITC conjugated
    Biotin CSB-PA845159LD01HU ASZ1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
  • 基因功能参考文献：
    1. Data reveal a potential role of GASZ during embryonic germ cell development and provide a powerful in vitro system for dissecting the molecular pathways in early germ cell formation during embryogenesis. PMID: 23816659
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
  • 数据库链接：

    HGNC: 1350

    OMIM: 605797

    KEGG: hsa:136991

    STRING: 9606.ENSP00000284629

    UniGene: Hs.352412