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ASZ1 Antibody

  • 货号：
    CSB-PA002256GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8WWH4
  • 基因名：
    ASZ1
  • 别名：
    ASZ1 antibody; ALP1 antibody; ANKL1 antibody; C7orf7 antibody; GASZAnkyrin repeat antibody; SAM and basic leucine zipper domain-containing protein 1 antibody; Ankyrin-like protein 1 antibody; Germ cell-specific ankyrin antibody; SAM and basic leucine zipper domain-containing protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ASZ1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
  • 基因功能参考文献：
    1. Data reveal a potential role of GASZ during embryonic germ cell development and provide a powerful in vitro system for dissecting the molecular pathways in early germ cell formation during embryogenesis. PMID: 23816659
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
  • 数据库链接：

    HGNC: 1350

    OMIM: 605797

    KEGG: hsa:136991

    STRING: 9606.ENSP00000284629

    UniGene: Hs.352412