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BUD13 Antibody

  • 货号：
    CSB-PA863104LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA863104LA01HU diluted at 1:500 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of U251 cells with CSB-PA863104LA01HU at 1:250, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) BUD13 Polyclonal antibody
  • Uniprot No.：
    Q9BRD0
  • 基因名：
    BUD13
  • 别名：
    Bud13 antibody; BUD13 homolog (S. cerevisiae) antibody; BUD13 homolog antibody; BUD13_HUMAN antibody; Cwc26 antibody; FLJ27090 antibody; fSAP71 antibody; Functional spliceosome-associated protein 71 antibody; MGC13125 antibody; OTTHUMP00000042639 antibody; OTTHUMP00000042640 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human BUD13 homolog protein (132-233AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，BUD13 Antibody (CSB-PA863104LA01HU)，的标记方式是Non-conjugated。对于BUD13 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863104LB01HU BUD13 Antibody, HRP conjugated ELISA
    FITC CSB-PA863104LC01HU BUD13 Antibody, FITC conjugated
    Biotin CSB-PA863104LD01HU BUD13 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
    IF 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in pre-mRNA splicing as component of the activated spliceosome.
  • 基因功能参考文献：
    1. Data concluded that novel mutations in BUD13 did not confer risk for MetS in our study population, but these mutations changed the level of metabolic complements. PMID: 28659142
    2. by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (Pcombined = 9.7 x 10(-22) ) in Han Chinese PMID: 28371326
    3. When the inter-dependence between alleles was examined using conditional models, five loci on BUD13, ZNF259, and ApoA5 showed possible independent associations. PMID: 26634697
    4. Single nucleotide polymorphisms (Rs17119975) of BUD13 protein did not increase the risk of CHD in the Chinese population. PMID: 26397108
    5. Common SNPs within the BUD13-APOA5 gene region can effect triglyceride and LDL cholesterol response to statin therapy. PMID: 25900265
    6. Single nucleotide polymorphism bud13 gene is associated with hyperlipidaemia. PMID: 24780069
    7. Significant linkage disequilibria were noted among ZNF259, BUD13 and MLXIPL SNPs and serum lipid levels. PMID: 24989072

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    CWC26 family
  • 数据库链接：

    HGNC: 28199

    KEGG: hsa:84811

    STRING: 9606.ENSP00000260210

    UniGene: Hs.437341