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  4. Recombinant Human BUD13 homolog (BUD13)

Recombinant Human BUD13 homolog (BUD13)

  • 中文名称：
    Recombinant Human BUD13 homolog(BUD13),Yeast
  • 货号：
    CSB-YP863104HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human BUD13 homolog(BUD13),Yeast
  • 货号：
    CSB-EP863104HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human BUD13 homolog(BUD13),Yeast
  • 货号：
    CSB-EP863104HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human BUD13 homolog(BUD13),Yeast
  • 货号：
    CSB-BP863104HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human BUD13 homolog(BUD13),Yeast
  • 货号：
    CSB-MP863104HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    BUD13
  • Uniprot No.：
  • 别名：
    Bud13; BUD13 homolog (S. cerevisiae); BUD13 homolog; BUD13_HUMAN; Cwc26; FLJ27090; fSAP71; Functional spliceosome-associated protein 71; MGC13125; OTTHUMP00000042639; OTTHUMP00000042640
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-619
  • 氨基酸序列
    MAAAPPLSKA EYLKRYLSGA DAGVDRGSES GRKRRKKRPK PGGAGGKGMR IVDDDVSWTA ISTTKLEKEE EEDDGDLPVV AEFVDERPEE VKQMEAFRSS AKWKLLGGHN EDLPSNRHFR HDTPDSSPRR VRHGTPDPSP RKDRHDTPDP SPRRARHDTP DPSPLRGARH DSDTSPPRRI RHDSSDTSPP RRARHDSPDP SPPRRPQHNS SGASPRRVRH DSPDPSPPRR ARHGSSDISS PRRVHNNSPD TSRRTLGSSD TQQLRRARHD SPDLAPNVTY SLPRTKSGKA PERASSKTSP HWKESGASHL SFPKNSKYEY DPDISPPRKK QAKSHFGDKK QLDSKGDCQK ATDSDLSSPR HKQSPGHQDS DSDLSPPRNR PRHRSSDSDL SPPRRRQRTK SSDSDLSPPR RSQPPGKKAA HMYSGAKTGL VLTDIQREQQ ELKEQDQETM AFEAEFQYAE TVFRDKSGRK RNLKLERLEQ RRKAEKDSER DELYAQWGKG LAQSRQQQQN VEDAMKEMQK PLARYIDDED LDRMLREQER EGDPMANFIK KNKAKENKNK KVRPRYSGPA PPPNRFNIWP GYRWDGVDRS NGFEQKRFAR LASKKAVEEL AYKWSVEDM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in pre-mRNA splicing as component of the activated spliceosome.
  • 基因功能参考文献：
    1. Data concluded that novel mutations in BUD13 did not confer risk for MetS in our study population, but these mutations changed the level of metabolic complements. PMID: 28659142
    2. by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (Pcombined = 9.7 x 10(-22) ) in Han Chinese PMID: 28371326
    3. When the inter-dependence between alleles was examined using conditional models, five loci on BUD13, ZNF259, and ApoA5 showed possible independent associations. PMID: 26634697
    4. Single nucleotide polymorphisms (Rs17119975) of BUD13 protein did not increase the risk of CHD in the Chinese population. PMID: 26397108
    5. Common SNPs within the BUD13-APOA5 gene region can effect triglyceride and LDL cholesterol response to statin therapy. PMID: 25900265
    6. Single nucleotide polymorphism bud13 gene is associated with hyperlipidaemia. PMID: 24780069
    7. Significant linkage disequilibria were noted among ZNF259, BUD13 and MLXIPL SNPs and serum lipid levels. PMID: 24989072

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    CWC26 family
  • 数据库链接：

    HGNC: 28199

    KEGG: hsa:84811

    STRING: 9606.ENSP00000260210

    UniGene: Hs.437341