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CA10 Antibody

  • 货号：
    CSB-PA941852
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA941852(CA10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9NS85
  • 基因名：
    CA10
  • 别名：
    CA 10 antibody; CA-RP X antibody; CA10 antibody; CAH10_HUMAN antibody; Carbonic anhydrase related protein antibody; Carbonic anhydrase-related protein 10 antibody; Carbonic anhydrase-related protein X antibody; CARP X antibody; CARPX antibody; Cerebral protein 15 antibody; HUCEP 15 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human CA10
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Does not have a catalytic activity.
  • 基因功能参考文献：
    1. Total heterogeneous methylation of CA10 conferred a significantly higher risk of Colorectal Cancer.The gene methylation status of blood leukocytes may be associated with CRC risk. PMID: 29291617
    2. The changes in the ratios of mRNA levels and the respective proteins (HIF-1alpha, HIF-2, NF-kB, VEGF, VEGFR2, and carboanhydrase IX) may contribute to kidney-cancer metastasis. PMID: 28537244
    3. Two African-ancestry specific variants were found to be significantly associated with metabolic syndrome S: SNP rs73989312[A] near CA10 that conferred increased risk; and SNP rs77244975[C] in CTNNA3 that conferred protection against this disease. PMID: 26507551
    4. Copy number deletion on CA10 was associated with a 1.69-fold decreased risk for osteoarthritis. PMID: 25880085
    5. our results suggest that genes CA10 and also SGK493 may be an important risk factor for asthma development, especially for a nonatopic phenotype. PMID: 24407380
    6. The results suggest that the variations of CA8 and CA10 loci may be important determinants of osteoporosis in Japanese women. PMID: 19172221
    7. Identifies a string of seven CCG repeats in the 5' UTR of a carbonic anhydrase X cDNA from human brain. PMID: 9921901

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  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 组织特异性：
    Strong expression in brain and central nervous system.
  • 数据库链接：

    HGNC: 1369

    OMIM: 604642

    KEGG: hsa:56934

    STRING: 9606.ENSP00000285273

    UniGene: Hs.463466