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  4. Recombinant Human Carbonic anhydrase-related protein 10 (CA10)

Recombinant Human Carbonic anhydrase-related protein 10 (CA10)

  • 中文名称：
    Recombinant Human Carbonic anhydrase-related protein 10(CA10),Yeast
  • 货号：
    CSB-YP878879HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Carbonic anhydrase-related protein 10(CA10),Yeast
  • 货号：
    CSB-EP878879HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Carbonic anhydrase-related protein 10(CA10),Yeast
  • 货号：
    CSB-EP878879HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Carbonic anhydrase-related protein 10(CA10),Yeast
  • 货号：
    CSB-BP878879HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Carbonic anhydrase-related protein 10(CA10),Yeast
  • 货号：
    CSB-MP878879HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CA10
  • Uniprot No.：
  • 别名：
    CA 10; CA-RP X; CA10; CAH10_HUMAN; Carbonic anhydrase related protein; Carbonic anhydrase-related protein 10; Carbonic anhydrase-related protein X; CARP X; CARPX; Cerebral protein 15; HUCEP 15
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-328
  • 氨基酸序列
    MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW GLVNSAWNLC SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN TGRHVSLRLD KEHLVNISGG PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ AFSGEVQLIH YNHELYTNVT EAAKSPNGLV VVSIFIKVSD SSNPFLNRML NRDTITRITY KNDAYLLQGL NIEELYPETS SFITYDGSMT IPPCYETASW IIMNKPVYIT RMQMHSLRLL SQNQPSQIFL SMSDNFRPVQ PLNNRCIRTN INFSLQGKDC PNNRAQKLQY RVNEWLLK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Does not have a catalytic activity.
  • 基因功能参考文献：
    1. Total heterogeneous methylation of CA10 conferred a significantly higher risk of Colorectal Cancer.The gene methylation status of blood leukocytes may be associated with CRC risk. PMID: 29291617
    2. The changes in the ratios of mRNA levels and the respective proteins (HIF-1alpha, HIF-2, NF-kB, VEGF, VEGFR2, and carboanhydrase IX) may contribute to kidney-cancer metastasis. PMID: 28537244
    3. Two African-ancestry specific variants were found to be significantly associated with metabolic syndrome S: SNP rs73989312[A] near CA10 that conferred increased risk; and SNP rs77244975[C] in CTNNA3 that conferred protection against this disease. PMID: 26507551
    4. Copy number deletion on CA10 was associated with a 1.69-fold decreased risk for osteoarthritis. PMID: 25880085
    5. our results suggest that genes CA10 and also SGK493 may be an important risk factor for asthma development, especially for a nonatopic phenotype. PMID: 24407380
    6. The results suggest that the variations of CA8 and CA10 loci may be important determinants of osteoporosis in Japanese women. PMID: 19172221
    7. Identifies a string of seven CCG repeats in the 5' UTR of a carbonic anhydrase X cDNA from human brain. PMID: 9921901

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  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 组织特异性：
    Strong expression in brain and central nervous system.
  • 数据库链接：

    HGNC: 1369

    OMIM: 604642

    KEGG: hsa:56934

    STRING: 9606.ENSP00000285273

    UniGene: Hs.463466