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CNTN6 Antibody

  • 货号：
    CSB-PA891801LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: CNTN6 antibody at 2.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 114 kDa
      Observed band size: 114 kDa
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA891801LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CNTN6 Polyclonal antibody
  • Uniprot No.：
    Q9UQ52
  • 基因名：
    CNTN6
  • 别名：
    CNTN 6 antibody; CNTN6 antibody; CNTN6_HUMAN antibody; Contactin 6 precursor antibody; Contactin-6 antibody; Contactin6 antibody; hNB 3 antibody; hNB-3 antibody; hNB3 antibody; MGC133256 antibody; NB 3 antibody; NB3 antibody; Neural adhesion molecule antibody; Neural recognition molecule NB 3 antibody; Neural recognition molecule NB-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Contactin-6 protein (706-812AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CNTN6 Antibody (CSB-PA891801LA01HU)，的标记方式是Non-conjugated。对于CNTN6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA891801LB01HU CNTN6 Antibody, HRP conjugated ELISA
    FITC CSB-PA891801LC01HU CNTN6 Antibody, FITC conjugated
    Biotin CSB-PA891801LD01HU CNTN6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
  • 基因功能参考文献：
    1. Clinical investigations of the patients carrying CNTN5 or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway. PMID: 27166760
    2. CNTN6 copy number variants (duplications) were associated with increased risk of Tourette syndrome. PMID: 28641109
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Immunoglobulin superfamily, Contactin family
  • 组织特异性：
    Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
  • 数据库链接：

    HGNC: 2176

    OMIM: 607220

    KEGG: hsa:27255

    STRING: 9606.ENSP00000341882

    UniGene: Hs.387300