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CTPS2 Antibody

  • 货号：
    CSB-PA006177GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NRF8
  • 基因名：
    CTPS2
  • 别名：
    CTP synthase 2 antibody; CTP synthase II antibody; CTP synthetase 2 antibody; CTPS2 antibody; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2 antibody; FLJ43358 antibody; MGC32997 antibody; PYRG2_HUMAN antibody; UTP--ammonia ligase 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human CTPS2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
  • 基因功能参考文献：
    1. CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin. PMID: 21252287
    2. Low CTPS2 expression may be a rationally-based determinant of 5FU resistance. PMID: 21378502
    3. analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275
  • 蛋白家族：
    CTP synthase family
  • 数据库链接：

    HGNC: 2520

    OMIM: 300380

    KEGG: hsa:56474

    STRING: 9606.ENSP00000352222

    UniGene: Hs.227049