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CTPS2 Antibody

  • 货号：
    CSB-PA865117EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunoprecipitating CTPS2 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA865117EA01HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA865117EA01HU (6µg) + HepG2 whole cell lysate (500µg)
      Lane 3: HepG2 whole cell lysate (20µg)
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: CTPS2 antibody at 2.8µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 66 kDa
      Observed band size: 66 kDa
    • Immunocytochemistry analysis of human gastric cancer using CSB-PA865117EA01HU at dilution of 1:100
    • Immunocytochemistry analysis of human prostate tissue using CSB-PA865117EA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CTPS2 Polyclonal antibody
  • Uniprot No.：
    Q9NRF8
  • 基因名：
    CTPS2
  • 别名：
    CTP synthase 2 antibody; CTP synthase II antibody; CTP synthetase 2 antibody; CTPS2 antibody; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2 antibody; FLJ43358 antibody; MGC32997 antibody; PYRG2_HUMAN antibody; UTP--ammonia ligase 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human CTP synthase 2 protein (62-315AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CTPS2 Antibody (CSB-PA865117EA01HU)，的标记方式是Non-conjugated。对于CTPS2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA865117EB01HU CTPS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA865117EC01HU CTPS2 Antibody, FITC conjugated
    Biotin CSB-PA865117ED01HU CTPS2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
  • 基因功能参考文献：
    1. CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin. PMID: 21252287
    2. Low CTPS2 expression may be a rationally-based determinant of 5FU resistance. PMID: 21378502
    3. analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275
  • 蛋白家族：
    CTP synthase family
  • 数据库链接：

    HGNC: 2520

    OMIM: 300380

    KEGG: hsa:56474

    STRING: 9606.ENSP00000352222

    UniGene: Hs.227049