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Chc Antibody

  • 中文名称:
    Chc兔多克隆抗体
  • 货号:
    CSB-PA333472XA01DLU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: Chc Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
  • 其他:

产品详情

  • Uniprot No.:
    P29742
  • 基因名:
    Chc
  • 别名:
    Clathrin heavy chain Chc CG9012
  • 反应种属:
    Drosophila melanogaster (Fruit fly)
  • 免疫原:
    Recombinant Drosophila melanogaster (Fruit fly) Chc protein (1-260aa)
  • 免疫原种属:
    Drosophila melanogaster (Fruit fly)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    Affinity-chromatography
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, WB
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
  • 基因功能参考文献:
    1. Bic-D is also required to transport Chc mRNA into the oocyte and for transport and proper localization of Chc protein to the oocyte cortex. PMID: 24718986
    2. Results report a Drosophila disabled (DAB)mutant revealing a novel role for DAB proteins in chemical synaptic transmission, and support a role for clathrin-mediated endocytosis in rapid clearance of neurotransmitter release sites. PMID: 21606364
    3. Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling. PMID: 20111007
    4. chc mRNA and protein are highly expressed from early stages of embryogenesis onwards, consistent with genetic studies predicting a maternal contribution of the gene function PMID: 19577664
    5. Chc is critical for synaptic vesicle recycling and in the absence of the protein, bulk retrieval mediates massive synaptic membrane internalization. PMID: 18762582

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  • 亚细胞定位:
    Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
  • 蛋白家族:
    Clathrin heavy chain family
  • 数据库链接:

    KEGG: dme:Dmel_CG9012

    STRING: 7227.FBpp0073966

    UniGene: Dm.3174