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DEPP1 Antibody

  • 货号：
    CSB-PA865135LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA865135LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA865135LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DEPP1 Polyclonal antibody
  • Uniprot No.：
    Q9NTK1
  • 基因名：
    DEPP1
  • 别名：
    Decidual protein induced by progesterone antibody; Depp antibody; DEPP_HUMAN antibody; Fasting-induced gene protein antibody; FIG antibody; Protein DEPP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein DEPP1 protein (57-174AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DEPP1 Antibody (CSB-PA865135LA01HU)，的标记方式是Non-conjugated。对于DEPP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA865135LB01HU DEPP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA865135LC01HU DEPP1 Antibody, FITC conjugated
    Biotin CSB-PA865135LD01HU DEPP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
  • 基因功能参考文献：
    1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
    2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
    3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
    4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
    5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
    6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073

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  • 亚细胞定位：
    Cytoplasm. Peroxisome. Mitochondrion.
  • 组织特异性：
    Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
  • 数据库链接：

    HGNC: 23355

    OMIM: 611309

    KEGG: hsa:11067

    STRING: 9606.ENSP00000298295

    UniGene: Hs.93675