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  4. Recombinant Human Protein DEPP (DEPP)

Recombinant Human Protein DEPP (DEPP)

  • 中文名称：
    Recombinant Human Protein DEPP(DEPP),Yeast
  • 货号：
    CSB-YP865135HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Protein DEPP(DEPP),Yeast
  • 货号：
    CSB-EP865135HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Protein DEPP(DEPP),Yeast
  • 货号：
    CSB-EP865135HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Protein DEPP(DEPP),Yeast
  • 货号：
    CSB-BP865135HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Protein DEPP(DEPP),Yeast
  • 货号：
    CSB-MP865135HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DEPP1
  • Uniprot No.：
  • 别名：
    Decidual protein induced by progesterone; Depp; DEPP_HUMAN; Fasting-induced gene protein; FIG; Protein DEPP
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-212
  • 氨基酸序列
    MRSRLLLSVA HLPTIRETTE EMLLGGPGQE PPPSPSLDDY VRSISRLAQP TSVLDKATAQ GQPRPPHRPA QACRKGRPAV SLRDITARFS GQQPTLPMAD TVDPLDWLFG ESQEKQPSQR DLPRRTGPSA GLWGPHRQMD SSKPMGAPRG RLCEARMPGH SLARPPQDGQ QSSDLRSWTF GQSAQAMASR HRPRPSSVLR TLYSHLPVIH EL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
  • 基因功能参考文献：
    1. Knockdown of DEPP prevented the primary and secondary reactive oxygen species wave during FOXO3 activation. PMID: 25261981
    2. C10orf10 expression is frequently decreased in breast cancer tissues and is associated with shorter survival times. PMID: 24936657
    3. DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells PMID: 21510935
    4. DEPP is a novel insulin-regulatory molecule expressed abundantly in insulin-sensitive tissues including white adipose tissue and liver. PMID: 19937567
    5. Expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart, unexpected degree of molecular heterogeneity among arterial endothelial cells, up-regulated in subsets of endothelial cells. PMID: 15977181
    6. Depp modulates the effects of progesterone during decidualization and in the decidua by affecting gene expression. PMID: 16123073

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  • 亚细胞定位：
    Cytoplasm. Peroxisome. Mitochondrion.
  • 组织特异性：
    Expressed in various tissues, including pancreas, placenta, ovary, testis and kidney.
  • 数据库链接：

    HGNC: 23355

    OMIM: 611309

    KEGG: hsa:11067

    STRING: 9606.ENSP00000298295

    UniGene: Hs.93675