DNAI1 Antibody
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货号:CSB-PA006997GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q9UI46
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基因名:DNAI1
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别名:Axonemal dynein intermediate chain 1 antibody; Axonemal dynein intermediate chain 2 antibody; CILD 1 antibody; CILD1 antibody; Cytoplasmic dynein 1 intermediate chain 1 antibody; Cytoplasmic dynein 1 intermediate chain 2 antibody; Cytoplasmic dynein intermediate chain 1 antibody; Cytoplasmic dynein intermediate chain 2 antibody; DH IC 1 antibody; DH IC 2 antibody; DIC1 antibody; DNAI 1 antibody; DNAI 2 antibody; DNAI1 antibody; DNAI1_HUMAN antibody; DNAI2 antibody; DNCI 2 antibody; DNCI1 antibody; DNCI2 antibody; DNCIC 1 antibody; DNCIC 2 antibody; DNCIC1 antibody; DNCIC2 antibody; Dynein axonemal intermediate chain 1 antibody; Dynein axonemal intermediate polypeptide 1 antibody; Dynein axonemal intermediate polypeptide 2 antibody; Dynein cytoplasmic intermediate polypeptide 1 antibody; Dynein cytoplasmic intermediate polypeptide 2 antibody; Dynein intermediate chain 1 axonemal antibody; Dynein intermediate chain 1 cytosolic antibody; Dynein intermediate chain 1; axonemal antibody; Dynein intermediate chain 2 axonemal antibody; Dynein intermediate chain 2 cytosolic antibody; Dynein intermediate chain DNAI1 antibody; IC74 antibody; ICS antibody; ICS1 antibody; Immotile cilia syndrome 1 antibody; MGC26204 antibody; PCD antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human DNAI1
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Part of the dynein complex of respiratory cilia.
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基因功能参考文献:
- A novel mutation causing primary ciliary dyskinesia was found in Japanese patients. PMID: 28939216
- The worldwide involvement of DNAI1 mutations in PCD pathogenesis in families not preselected for ODA defects ranges from 7 to 10%. PMID: 21143860
- A total of 10% of patients with PCD are estimated to harbor mutations in DNAI1; most occur as a common founder IVS1+2_3insT or in exons 13, 16, and 17. PMID: 16858015
- DNAI1 gene mutation is not a common cause of primary ciliary dyskinesia. PMID: 18434704
- Two dynein genes, encoding ODA intermediate chain (DNAI1) and heavy chain (DNAH5), have been seen to be mutated in approximately 30-38% of the families PMID: 19300264
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相关疾病:Ciliary dyskinesia, primary, 1 (CILD1); Kartagener syndrome (KTGS)
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亚细胞定位:Dynein axonemal particle. Cytoplasm, cytoskeleton, cilium axoneme.
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蛋白家族:Dynein intermediate chain family
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组织特异性:Expressed in respiratory ciliated cells (at protein level).
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数据库链接:
HGNC: 2954
OMIM: 244400
KEGG: hsa:27019
STRING: 9606.ENSP00000242317
UniGene: Hs.112667
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