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ESAM Antibody

  • 货号：
    CSB-PA850258LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA850258LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ESAM Polyclonal antibody
  • Uniprot No.：
    Q96AP7
  • 基因名：
  • 别名：
    2310008D05Rik antibody; Endothelial cell adhesion molecule antibody; Endothelial cell selective adhesion molecule antibody; Endothelial cell-selective adhesion molecule antibody; Esam antibody; ESAM_HUMAN antibody; HUEL (C4orf1) interacting protein antibody; LP4791 protein antibody; W117m antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Endothelial cell-selective adhesion molecule protein (30-248AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ESAM Antibody (CSB-PA850258LA01HU)，的标记方式是Non-conjugated。对于ESAM Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA850258LB01HU ESAM Antibody, HRP conjugated ELISA
    FITC CSB-PA850258LC01HU ESAM Antibody, FITC conjugated
    Biotin CSB-PA850258LD01HU ESAM Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can mediate aggregation most likely through a homophilic molecular interaction.
  • 基因功能参考文献：
    1. sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID: 26523992
    2. ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID: 26774386
    3. Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID: 24456423
    4. sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID: 24177327
    5. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID: 20153339
    6. sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID: 19759376

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  • 亚细胞定位：
    Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Highly expressed in endothelial cells.
  • 数据库链接：

    HGNC: 17474

    OMIM: 614281

    KEGG: hsa:90952

    STRING: 9606.ENSP00000278927

    UniGene: Hs.173840