Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. ESAM Antibody

ESAM Antibody

  • 货号：
    CSB-PA007818GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96AP7
  • 基因名：
  • 别名：
    2310008D05Rik antibody; Endothelial cell adhesion molecule antibody; Endothelial cell selective adhesion molecule antibody; Endothelial cell-selective adhesion molecule antibody; Esam antibody; ESAM_HUMAN antibody; HUEL (C4orf1) interacting protein antibody; LP4791 protein antibody; W117m antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ESAM
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can mediate aggregation most likely through a homophilic molecular interaction.
  • 基因功能参考文献：
    1. sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID: 26523992
    2. ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID: 26774386
    3. Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID: 24456423
    4. sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID: 24177327
    5. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID: 20153339
    6. sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID: 19759376

    显示更多

    收起更多

  • 亚细胞定位：
    Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Highly expressed in endothelial cells.
  • 数据库链接：

    HGNC: 17474

    OMIM: 614281

    KEGG: hsa:90952

    STRING: 9606.ENSP00000278927

    UniGene: Hs.173840