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FAM129A Antibody

  • 货号：
    CSB-PA008049GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BZQ8
  • 基因名：
    FAM129A
  • 别名：
    NIBAN1 antibody; C1orf24 antibody; FAM129A antibody; NIBAN antibody; GIG39 antibody; Protein Niban 1 antibody; Cell growth-inhibiting gene 39 protein antibody; Protein FAM129A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human FAM129A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.
  • 基因功能参考文献：
    1. Data suggest that decreasing C1orf24 protein levels by restoring microRNA miR-106b function may have therapeutic implications. PMID: 26317551
    2. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    3. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    4. The expression of Niban frequently begins in the early stages of head and neck squamous carcinoma and remains upregulated throughout the carcinogenic process. Niban may be a good molecular marker of HNSCC. PMID: 19536772
    5. Niban expression is up-regulated in various types of thyroid tumors. PMID: 16949643

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  • 亚细胞定位：
    Cytoplasm. Membrane; Lipid-anchor.
  • 蛋白家族：
    Niban family
  • 组织特异性：
    Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with
  • 数据库链接：

    HGNC: 16784

    KEGG: hsa:116496

    STRING: 9606.ENSP00000356481

    UniGene: Hs.518662