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  4. Phospho-FAM129A (Ser602) Antibody

Phospho-FAM129A (Ser602) Antibody

  • 货号：
    CSB-PA589975
  • 规格：
    ￥2454
  • 图片：
    • Western blot analysis in vitro kinase assays were performed by mixing purified bacterially expressed WT His-Niban or the His-Niban S602A with or without purified active AKT1 using Niban (Phospho-Ser602) Antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FAM129A Polyclonal antibody
  • Uniprot No.：
    Q9BZQ8
  • 基因名：
    FAM129A
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Peptide sequence around phosphorylation site of serine 602 (R-A-S(p)-A-I) derived from Human Niban.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.
  • 基因功能参考文献：
    1. Data suggest that decreasing C1orf24 protein levels by restoring microRNA miR-106b function may have therapeutic implications. PMID: 26317551
    2. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    3. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    4. The expression of Niban frequently begins in the early stages of head and neck squamous carcinoma and remains upregulated throughout the carcinogenic process. Niban may be a good molecular marker of HNSCC. PMID: 19536772
    5. Niban expression is up-regulated in various types of thyroid tumors. PMID: 16949643

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  • 亚细胞定位：
    Cytoplasm. Membrane; Lipid-anchor.
  • 蛋白家族：
    Niban family
  • 组织特异性：
    Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with
  • 数据库链接：

    HGNC: 16784

    KEGG: hsa:116496

    STRING: 9606.ENSP00000356481

    UniGene: Hs.518662