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FOXP4 Antibody

  • 货号：
    CSB-PA825220
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extract from JK and Hela cells using FOXP4 Antibody
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FOXP4 Polyclonal antibody
  • Uniprot No.：
    Q8IVH2
  • 基因名：
    FOXP4
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Peptide sequence around aa.7~11(S-E-T-I-R) derived from Human FOXP4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor that represses lung-specific expression.
  • 基因功能参考文献：
    1. results indicated lncRNA MFI2 could promote proliferation and migration of osteosarcoma cells by regulating FOXP4 expression, which suggested critical roles of lncRNA MFI2 and FOXP4 in occurrence and development of human osteosarcoma PMID: 27513470
    2. FOXP4 and SHROOM1 genes are hypermethylated in the knee osteoarthritic cartilage. PMID: 26484395
    3. High FOXP4 expression is associated with non-small cell lung cancer. PMID: 25994569
    4. rs4714476 at the 5' near gene of FOXP4 potentially contributes to the susceptibility of prostate cancer in Chinese men PMID: 26642711
    5. These findings suggest that miR-338-3p regulates survival of hepatocellular carcinoma cells partially through the downregulation of FOXP4 PMID: 25755720
    6. Foxp4 is dispensable for T cell development, but necessary for normal T cell cytokine recall responses to antigen following pathogenic infection PMID: 22912696
    7. these data implicate specific members of the FOX family of TFs (FOXC1, C2, P1, P4, and O1A) not previously suggested in heart failure pathogenesis. PMID: 16952980
    8. Contrary to the current view, T cell receptor-mediated signals are not responsible for the induction of FOXP3 in human thymocytes. PMID: 18322169

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 20842

    OMIM: 608924

    KEGG: hsa:116113

    STRING: 9606.ENSP00000309823

    UniGene: Hs.131436