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GALNT7 Antibody

  • 中文名称：
    GALNT7兔多克隆抗体
  • 货号：
    CSB-PA009214GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q86SF2
  • 基因名：
    GALNT7
  • 别名：
    GalNAc T7 antibody; GalNAc-T7 antibody; GalNAcT7 antibody; GALNT 7 antibody; Galnt7 antibody; GALT7_HUMAN antibody; N acetylgalactosaminyltransferase 7 antibody; N-acetylgalactosaminyltransferase 7 antibody; Polypeptide GalNAc transferase 7 antibody; Polypeptide N acetylgalactosaminyltransferase 7 antibody; pp GaNTase 7 antibody; pp-GaNTase 7 antibody; Protein UDP acetylgalactosaminyltransferase 7 antibody; Protein-UDP acetylgalactosaminyltransferase 7 antibody; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human GALNT7
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
  • 基因功能参考文献：
    1. miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma. PMID: 26503214
    2. High expression of GALNT7 promotes migration and invasion and lymph node metastasis in esophageal squamous cell carcinoma. PMID: 27619677
    3. GALNT7 and CDK16 were confirmed to be the direct targets of miR-494. These results suggested that miR-494 play an inhibitory role in the tumorigenesis of NPC PMID: 25809707
    4. The study of miR-34a, miR-34c and its novel target, GALNT7, may serve as novel potential makers for laryngeal squamous cell carcinoma therapy. PMID: 24482044
    5. miR-214 is a new regulator of GALNT7, and both miR-214 and GALNT7 play important roles in the pathogenesis of cervical cancer PMID: 22399294
    6. Ectopic expression of miR-30b/30d promoted the metastatic behavior of melanoma cells by directly targeting the GalNAc transferase GALNT7. PMID: 21741600
    7. MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7 PMID: 19844573

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 组织特异性：
    Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
  • 数据库链接：

    HGNC: 4129

    OMIM: 605005

    KEGG: hsa:51809

    STRING: 9606.ENSP00000265000

    UniGene: Hs.548088