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GAS2L1 Antibody

  • 货号：
    CSB-PA859511ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA859511ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA859511ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GAS2L1 Polyclonal antibody
  • Uniprot No.：
    Q99501
  • 基因名：
    GAS2L1
  • 别名：
    GA2L1_HUMAN antibody; GAR 22 antibody; GAR22 antibody; GAS2 like protein 1 antibody; GAS2 related protein on chromosome 22 antibody; GAS2-like protein 1 antibody; GAS2-related protein on chromosome 22 antibody; GAS2L1 antibody; Growth arrest specific 2 like 1 antibody; Growth arrest specific protein 2 like 1 antibody; Growth arrest-specific protein 2-like 1 antibody; MGC17243 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human GAS2-like protein 1 protein (130-400AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers.
  • 基因功能参考文献：
    1. This work reveals a GAS2L1-mediated centriole-tethering mechanism of microtubules and actin, which provide the forces required for centrosome dynamics and separation. PMID: 28017616
    2. GAS2L1 and GAS2L2 are differentially involved in mediating the crosstalk between F-actin and microtubules. PMID: 24706950
    3. There was no significant difference in the frequency six marker haplotype in the GAS2L1 gene between the cases of schizophreina and controls. PMID: 20537721
    4. The beta isoforms of hGAR17 and hGAR22 appear to be able to crosslink microtubules and microfilaments PMID: 12584248
    5. T3-induced genes identified basic transcription element binding protein 1/Kruppel-like factor 9 (BTEB1/KLF9) and GAR22 as TR target genes PMID: 19375645

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
  • 蛋白家族：
    GAS2 family
  • 数据库链接：

    HGNC: 16955

    OMIM: 602128

    KEGG: hsa:10634

    STRING: 9606.ENSP00000344012

    UniGene: Hs.322852