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  4. Recombinant Human GAS2-like protein 1 (GAS2L1)

Recombinant Human GAS2-like protein 1 (GAS2L1)

  • 中文名称：
    人GAS2L1重组蛋白
  • 货号：
    CSB-YP859511HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人GAS2L1重组蛋白
  • 货号：
    CSB-EP859511HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人GAS2L1重组蛋白
  • 货号：
    CSB-EP859511HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人GAS2L1重组蛋白
  • 货号：
    CSB-BP859511HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人GAS2L1重组蛋白
  • 货号：
    CSB-MP859511HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    GAS2L1
  • Uniprot No.：
  • 别名：
    GA2L1_HUMAN; GAR 22; GAR22; GAS2 like protein 1; GAS2 related protein on chromosome 22 ; GAS2-like protein 1; GAS2-related protein on chromosome 22; GAS2L1; Growth arrest specific 2 like 1; Growth arrest specific protein 2 like 1; Growth arrest-specific protein 2-like 1; MGC17243
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-681
  • 氨基酸序列
    MADPVAGIAG SAAKSVRPFR SSEAYVEAMK EDLAEWLNAL YGLGLPGGGD GFLTGLATGT TLCQHANAVT EAARALAAAR PARGVAFQAH SVVPGSFMAR DNVATFIGWC RVELGVPEVL MFETEDLVLR KNEKSVVLCL LEVARRGARL GLLAPRLVQF EQEIERELRA APPAPNAPAA GEDTTETAPA PGTPARGPRM TPSDLRNLDE LVREILGRCT CPDQFPMIKV SEGKYRVGDS SLLIFVRVLR SHVMVRVGGG WDTLEHYLDK HDPCRCSSTA HRPPQPRVCT FSPQRVSPTT SPRPASPVPG SERRGSRPEM TPVSLRSTKE GPETPPRPRD QLPPHPRSRR YSGDSDSSAS SAQSGPLGTR SDDTGTGPRR ERPSRRLTTG TPASPRRPPA LRSQSRDRLD RGRPRGAPGG RGAQLSVPSP ARRARSQSRE EQAVLLVRRD RDGQHSWVPR GRGSGGSGRS TPQTPRARSP AAPRLSRVSS PSPELGTTPA SIFRTPLQLD PQQEQQLFRR LEEEFLANAR ALEAVASVTP TGPVPDPARA PDPPAPDSAY CSSSSSSSSL SVLGGKCGQP GDSGRTANGL PGPRSQALSS SSDEGSPCPG MGGPLDAPGS PLACTEPSRT WARGRMDTQP DRKPSRIPTP RGPRRPSGPA ELGTWHALHS VTPRAEPDSW M
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers.
  • 基因功能参考文献：
    1. This work reveals a GAS2L1-mediated centriole-tethering mechanism of microtubules and actin, which provide the forces required for centrosome dynamics and separation. PMID: 28017616
    2. GAS2L1 and GAS2L2 are differentially involved in mediating the crosstalk between F-actin and microtubules. PMID: 24706950
    3. There was no significant difference in the frequency six marker haplotype in the GAS2L1 gene between the cases of schizophreina and controls. PMID: 20537721
    4. The beta isoforms of hGAR17 and hGAR22 appear to be able to crosslink microtubules and microfilaments PMID: 12584248
    5. T3-induced genes identified basic transcription element binding protein 1/Kruppel-like factor 9 (BTEB1/KLF9) and GAR22 as TR target genes PMID: 19375645

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
  • 蛋白家族：
    GAS2 family
  • 数据库链接：

    HGNC: 16955

    OMIM: 602128

    KEGG: hsa:10634

    STRING: 9606.ENSP00000344012

    UniGene: Hs.322852