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GID8 Antibody

  • 中文名称：
    GID8兔多克隆抗体
  • 货号：
    CSB-PA882124LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA882124LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GID8 Polyclonal antibody
  • Uniprot No.：
    Q9NWU2
  • 基因名：
    GID8
  • 别名：
    GID8 antibody; C20orf11 antibody; TWA1Glucose-induced degradation protein 8 homolog antibody; Two hybrid-associated protein 1 with RanBPM antibody; Twa1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Glucose-induced degradation protein 8 homolog protein (1-228AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GID8 Antibody (CSB-PA882124LA01HU)，的标记方式是Non-conjugated。对于GID8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA882124LB01HU GID8 Antibody, HRP conjugated ELISA
    FITC CSB-PA882124LC01HU GID8 Antibody, FITC conjugated
    Biotin CSB-PA882124LD01HU GID8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
  • 基因功能参考文献：
    1. The results identify Twa1 as a previously undescribed regulator of the Wnt pathway for promoting colorectal tumorigenesis by facilitating beta-catenin nuclear retention. PMID: 28829046
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    GID8 family
  • 组织特异性：
    Up-regulated in colorectal cancer tissues (at protein level).
  • 数据库链接：

    HGNC: 15857

    OMIM: 611625

    KEGG: hsa:54994

    STRING: 9606.ENSP00000266069

    UniGene: Hs.353013