Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. HCN3 Antibody

HCN3 Antibody

  • 中文名称：
    HCN3兔多克隆抗体
  • 货号：
    CSB-PA010218GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9P1Z3
  • 基因名：
    HCN3
  • 别名：
    HCN3; KIAA1535; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HCN3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.
  • 基因功能参考文献：
    1. Reduced HCN3 expression in aganglionic bowel suggests its potential role in Hirschsprung's disease pathophysiology. PMID: 25987789
    2. KCTD3 is an accessory subunit of native HCN3 complexes PMID: 23382386
    3. Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 , HCN2, HCN3 and HCN4. PMID: 21615589
    4. human HCN3 is not modulated by intracellular cAMP, in contrast to other HCN subtypes PMID: 16043489
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel HCN family
  • 组织特异性：
    Detected in brain.
  • 数据库链接：

    HGNC: 19183

    OMIM: 609973

    KEGG: hsa:57657

    STRING: 9606.ENSP00000357342

    UniGene: Hs.706960