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HEXIM2 Antibody

  • 货号：
    CSB-PA010319LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat liver tissue, Mouse kidney tissue
      All lanes: HEXIM2 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA010319LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HEXIM2 Polyclonal antibody
  • Uniprot No.：
    Q96MH2
  • 基因名：
    HEXIM2
  • 别名：
    Hexamethylene bis-acetamide-inducible protein 2 antibody; Hexamthylene bis-acetamide inducible 2 antibody; HEXI2_HUMAN antibody; hexim 2 antibody; HEXIM2 antibody; L3 antibody; Protein HEXIM2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Protein HEXIM2 protein (1-286AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HEXIM2 Antibody (CSB-PA010319LA01HU)，的标记方式是Non-conjugated。对于HEXIM2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010319LB01HU HEXIM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA010319LC01HU HEXIM2 Antibody, FITC conjugated
    Biotin CSB-PA010319LD01HU HEXIM2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • 基因功能参考文献：
    1. HEXIM2 can functionally and quantitatively compensate for the loss of HEXIM1 PMID: 15713661
    2. utilization of HEXIM1 or HEXIM2 to bind and inhibit P-TEFb can be differentially regulated in vivo. PMID: 15713662
    3. Positive transcription elongation factor b regulates eukaryotic gene expression at the level of elongation and is controlled by the reversible association with HEXIM2. PMID: 15965233
    4. The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed. PMID: 19883659
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    HEXIM family
  • 组织特异性：
    Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
  • 数据库链接：

    HGNC: 28591

    OMIM: 615695

    KEGG: hsa:124790

    STRING: 9606.ENSP00000302276

    UniGene: Hs.56382