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KIZ Antibody

  • 货号：
    CSB-PA644808ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: KIZ antibody at 2.89µg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: A549 whole cell lysate
      Lane 3: CEM whole cell lysate
      Lane 4: Hela whole cell lysate
      Lane 5: Jurkat whole cell lysate
      Lane 6: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 76, 63, 70, 74, 60 kDa
      Observed band size: 76 kDa
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA644808ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA644808ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KIZ Polyclonal antibody
  • Uniprot No.：
    Q2M2Z5
  • 基因名：
    KIZ
  • 别名：
    Centrosomal protein kizuna antibody; DKFZP586H021 antibody; HT013 antibody; Kiz antibody; KIZ_HUMAN antibody; KIZUNA antibody; MGC102941 antibody; MGC141930 antibody; NCRNA00153 antibody; Plk1s1 antibody; Polo-like kinase 1 substrate 1 antibody; Uncharacterized protein C20orf19 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Centrosomal protein kizuna protein (1-240AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
  • 基因功能参考文献：
    1. Kiz phosphorylation depends on a balance between CDC25B and Plk1 activities. PMID: 25558830
    2. Immunohistology revealed KIZ localization at the basal body of the cilia in human fibroblasts, thus shedding light on another ciliary protein implicated in autosomal-recessive RCD PMID: 24680887
  • 相关疾病：
    Retinitis pigmentosa 69 (RP69)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Kizuna family
  • 数据库链接：

    HGNC: 15865

    OMIM: 615757

    KEGG: hsa:55857

    UniGene: Hs.187635