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LAMB Antibody

  • 货号：
    CSB-PA365810XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: LAMB antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29.8 kDa
      Observed band size: 31 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P02943
  • 基因名：
    LAMB
  • 别名：
    Maltoporin (Lambda receptor protein) (Maltose-inducible porin) lamB malB b4036 JW3996
  • 反应种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Escherichia coli (strain K12) LAMB protein
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the transport of maltose and maltodextrins. Indispensable for translocation of maltodextrins (alpha 1-4 linked polyglucosyls) containing more than three glucosyl moieties. A hydrophobic path ('greasy slide') of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda. Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility.
  • 基因功能参考文献：
    1. Our data indicate that the negative regulation by LamB is widely detected in antibiotic-resistant E. coli. LamB serves as a porin to influx an antibiotic and is interacted with Odp1. PMID: 24412198
    2. Results report the crystallization of E. coli maltoporin in a new crystal form; the crystals belonged to the trigonal R3 space group and diffracted to 1.9 A resolution. PMID: 21206039
    3. downregulation of LamB expression in the CTC-resistant E. coli strain and the increased antibiotic resistance in its gene-deleted strain suggested a negative regulation mechanism in E. coli in response to CTC PMID: 20718490
    4. demonstrated that LamB moves along the bacterial surface and that these movements are restricted by an underlying dynamic spiral pattern PMID: 15341654
    5. all aromatic residues provide some steric hindrance for ion transport through LamB PMID: 16095613

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  • 亚细胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Porin LamB (TC 1.B.3) family
  • 数据库链接：

    KEGG: ecj:JW3996

    STRING: 316385.ECDH10B_4225