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LDLRAD3 Antibody

  • 中文名称：
    LDLRAD3兔多克隆抗体
  • 货号：
    CSB-PA007326
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q86YD5
  • 基因名：
    LDLRAD3
  • 别名：
    LDLRAD3 antibody; LRAD3 antibody; Low-density lipoprotein receptor class A domain-containing protein 3 antibody; LDLR class A domain-containing protein 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human LDLRAD3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production.
  • 基因功能参考文献：
    1. Data suggest that circular RNA circ-LDLRAD3 may be a biomarker in the diagnosis of pancreatic cancer. PMID: 29307994
    2. LRAD3 that modulates amyloid precursor protein trafficking. PMID: 21795536
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    LDLR family
  • 组织特异性：
    Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver.
  • 数据库链接：

    HGNC: 27046

    KEGG: hsa:143458

    UniGene: Hs.745134