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MPP7 Antibody

  • 货号：
    CSB-PA014764GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q5T2T1
  • 基因名：
    MPP7
  • 别名：
    FLJ32798 antibody; MAGUK p55 subfamily member 7 antibody; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7 antibody; MPP7 antibody; MPP7_HUMAN antibody; Palmitoylated membrane protein 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MPP7
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
  • 基因功能参考文献：
    1. MPP7 as a novel candidate gene for Primary open angle glaucoma. PMID: 27001270
    2. The association of MPP7 single-nucleotide polymorphism rs4317882 gene variant with site-specific bone mineral density was determined. PMID: 22171069
    3. MPP7 is a PDZ protein that interacts with human papillomavirus-16 E6 and forms a tripartite complex with LIN7A or LIN7C and DLG1, regulating the stability and localization of DLG1 to cell junctions. PMID: 17237226
    4. MPP7 targets to the lateral surface of epithelial cells via its L27N domain, through an interaction with Dlg1. PMID: 17332497
  • 亚细胞定位：
    Membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm.
  • 蛋白家族：
    MAGUK family
  • 数据库链接：

    HGNC: 26542

    OMIM: 610973

    KEGG: hsa:143098

    STRING: 9606.ENSP00000337907

    UniGene: Hs.499159