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  4. Recombinant Human MAGUK p55 subfamily member 7 (MPP7)

Recombinant Human MAGUK p55 subfamily member 7 (MPP7)

  • 货号：
    CSB-YP719401HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP719401HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP719401HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP719401HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP719401HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MPP7
  • Uniprot No.：
  • 别名：
    FLJ32798; MAGUK p55 subfamily member 7; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7; MPP7; MPP7_HUMAN; Palmitoylated membrane protein 7
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-576
  • 氨基酸序列
    MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL VKIHEKLHYY EKQSPVPILH GAAALADDLA EELQNKPLNS EIRELLKLLS KPNVKALLSV HDTVAQKNYD PVLPPMPEDI DDEEDSVKII RLVKNREPLG ATIKKDEQTG AIIVARIMRG GAADRSGLIH VGDELREVNG IPVEDKRPEE IIQILAQSQG AITFKIIPGS KEETPSKEGK MFIKALFDYN PNEDKAIPCK EAGLSFKKGD ILQIMSQDDA TWWQAKHEAD ANPRAGLIPS KHFQERRLAL RRPEILVQPL KVSNRKSSGF RKSFRLSRKD KKTNKSMYEC KKSDQYDTAD VPTYEEVTPY RRQTNEKYRL VVLVGPVGVG LNELKRKLLI SDTQHYGVTV PHTTRARRSQ ESDGVEYIFI SKHLFETDVQ NNKFIEYGEY KNNYYGTSID SVRSVLAKNK VCLLDVQPHT VKHLRTLEFK PYVIFIKPPS IERLRETRKN AKIISSRDDQ GAAKPFTEED FQEMIKSAQI MESQYGHLFD KIIINDDLTV AFNELKTTFD KLETETHWVP VSWLHS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
  • 基因功能参考文献：
    1. MPP7 as a novel candidate gene for Primary open angle glaucoma. PMID: 27001270
    2. The association of MPP7 single-nucleotide polymorphism rs4317882 gene variant with site-specific bone mineral density was determined. PMID: 22171069
    3. MPP7 is a PDZ protein that interacts with human papillomavirus-16 E6 and forms a tripartite complex with LIN7A or LIN7C and DLG1, regulating the stability and localization of DLG1 to cell junctions. PMID: 17237226
    4. MPP7 targets to the lateral surface of epithelial cells via its L27N domain, through an interaction with Dlg1. PMID: 17332497
  • 亚细胞定位：
    Membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm.
  • 蛋白家族：
    MAGUK family
  • 数据库链接：

    HGNC: 26542

    OMIM: 610973

    KEGG: hsa:143098

    STRING: 9606.ENSP00000337907

    UniGene: Hs.499159