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MT1M Antibody

  • 货号：
    CSB-PA17429A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MT1M Polyclonal antibody
  • Uniprot No.：
    Q8N339
  • 基因名：
    MT1M
  • 别名：
    MT1M antibody; MT1K antibody; Metallothionein-1M antibody; MT-1M antibody; Metallothionein-IM antibody; MT-IM antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Metallothionein-1M protein (1-61AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，MT1M Antibody (CSB-PA17429A0Rb)，的标记方式是Non-conjugated。对于MT1M Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA17429B0Rb MT1M Antibody, HRP conjugated ELISA
    FITC CSB-PA17429C0Rb MT1M Antibody, FITC conjugated
    Biotin CSB-PA17429D0Rb MT1M Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
  • 基因功能参考文献：
    1. Results found that MT1M is downregulated in hepatocellular carcinoma (HCC) tumors, and it suppressed HCC tumorigenesis possibly by inducing cell cycle arrest, enhancing apoptosis and inhibiting cell migration and invasion. These findings provide evidence that MT1M might be a tumor suppressor in HCC tumorigenesis. PMID: 28380433
    2. Low MT1M expression is associated with poor hepatocellular carcinoma prognosis following curative resection. PMID: 27808371
    3. miR-24-3p plays an important role in the initiation and progression of hepatocellular carcinoma by targeting metallothionein 1M. PMID: 27650047
    4. Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas. PMID: 22971577
  • 蛋白家族：
    Metallothionein superfamily, Type 1 family
  • 数据库链接：

    HGNC: 14296

    OMIM: 156357

    KEGG: hsa:4499

    STRING: 9606.ENSP00000369146

    UniGene: Hs.647370